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hydrochlorothiazide and quinapril

Pronunciation: HYE droe KLOR oh THY a zide and KWIN a pril

Brand: Accuretic

Accuretic

slide 1 of 13, Accuretic,

12.5 mg-10 mg, oval, pink, imprinted with PD 222

Image of Accuretic
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Hydrochlorothiazide-Quinapril Hydrochloride

slide 2 of 13, Hydrochlorothiazide-Quinapril Hydrochloride,

12.5 mg-20 mg, oval, pink, imprinted with I G, 375

Image of Hydrochlorothiazide-Quinapril Hydrochloride
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Hydrochlorothiazide-Quinapril Hydrochloride

slide 3 of 13, Hydrochlorothiazide-Quinapril Hydrochloride,

12.5 mg-20 mg, triangular, pink, imprinted with G 220

Image of Hydrochlorothiazide-Quinapril Hydrochloride
slide 3 of 13
    

Hydrochlorothiazide-Quinapril Hydrochloride

slide 4 of 13, Hydrochlorothiazide-Quinapril Hydrochloride,

12.5 mg-10 mg, oval, pink, imprinted with G 222

Image of Hydrochlorothiazide-Quinapril Hydrochloride
slide 4 of 13
    

Hydrochlorothiazide-Quinapril Hydrochloride

slide 5 of 13, Hydrochlorothiazide-Quinapril Hydrochloride,

25 mg-20 mg, round, pink, imprinted with G 223

Image of Hydrochlorothiazide-Quinapril Hydrochloride
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Accuretic

slide 6 of 13, Accuretic,

12.5 mg-20 mg, triangular, pink, imprinted with PD 220

Image of Accuretic
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Accuretic

slide 7 of 13, Accuretic,

25 mg-20 mg, round, pink, imprinted with PD 223

Image of Accuretic
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Hydrochlorothiazide-Quinapril Hydrochloride

slide 8 of 13, Hydrochlorothiazide-Quinapril Hydrochloride,

12.5 mg-10 mg, round, pink, imprinted with M 542

Image of Hydrochlorothiazide-Quinapril Hydrochloride
slide 8 of 13
    

Hydrochlorothiazide-Quinapril Hydrochloride

slide 9 of 13, Hydrochlorothiazide-Quinapril Hydrochloride,

12.5 mg-20 mg, round, yellow, imprinted with M 543

Image of Hydrochlorothiazide-Quinapril Hydrochloride
slide 9 of 13
    

Hydrochlorothiazide-Quinapril Hydrochloride

slide 10 of 13, Hydrochlorothiazide-Quinapril Hydrochloride,

25 mg-20 mg, round, pink, imprinted with M 544

Image of Hydrochlorothiazide-Quinapril Hydrochloride
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Quinaretic

slide 11 of 13, Quinaretic,

12.5 mg-10 mg, oval, peach, imprinted with A2 38

Image of Quinaretic
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Quinaretic

slide 12 of 13, Quinaretic,

12.5 mg-20 mg, triangular, peach, imprinted with A 239

Image of Quinaretic
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Quinaretic

slide 13 of 13, Quinaretic,

25 mg-20 mg, round, orange, imprinted with A 240

Image of Quinaretic
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What is the most important information I should know about hydrochlorothiazide and quinapril?

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.

You should not use this medicine if you have ever had angioedema, if you are unable to urinate, or if you are allergic to sulfa drugs or to any ACE inhibitor. Do not take hydrochlorothiazide and quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use hydrochlorothiazide and quinapril together with any medication that contains aliskiren (a blood pressure medicine).

What is hydrochlorothiazide and quinapril?

Hydrochlorothiazide is a thiazide diuretic (water pill). Quinapril is in an ACE inhibitor (ACE stands for angiotensin converting enzyme).

Hydrochlorothiazide and quinapril is a combination medicine used to treat hypertension (high blood pressure). Lowering blood pressure may lower your risk of a stroke or heart attack.

Hydrochlorothiazide and quinapril may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking hydrochlorothiazide and quinapril?

You should not use this medicine if you are allergic to hydrochlorothiazide or quinapril, or if:

  • you have a history of angioedema;
  • you are unable to urinate;
  • you recently took a heart medicine called sacubitril; or
  • you have ever had a severe allergic reaction to any ACE inhibitor (benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril).

Do not take hydrochlorothiazide and quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use hydrochlorothiazide and quinapril together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking hydrochlorothiazide and quinapril with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

  • kidney disease (or if you are on dialysis);
  • cirrhosis or other liver disease;
  • glaucoma;
  • congestive heart failure;
  • gout;
  • lupus;
  • an allergy to sulfa drugs or penicillin; or
  • if you are on a low-salt diet.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Quinapril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using hydrochlorothiazide and quinapril.

Hydrochlorothiazide and quinapril is not approved for use by anyone younger than 18 years old.

How should I take hydrochlorothiazide and quinapril?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.

Your blood pressure will need to be checked often, and you may need occasional blood tests.

If you need surgery, tell your surgeon you currently use this medicine.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking hydrochlorothiazide and quinapril?

Drinking alcohol can further lower your blood pressure and may increase certain side effects of this medicine.

Do not use salt substitutes or potassium supplements while taking this medicine, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

What are the possible side effects of hydrochlorothiazide and quinapril?

Get emergency medical help if you have signs of an allergic reaction (hives, severe stomach pain, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • eye pain, vision problems;
  • swelling, weight gain, shortness of breath;
  • sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, trouble swallowing;
  • high potassium --nausea, tingly feeling, chest pain, irregular heartbeats, loss of movement;
  • low potassium level --leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling; or
  • low levels of sodium --headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady.

Common side effects may include:

  • cough;
  • headache, dizziness;
  • tired feeling; or
  • muscle pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect hydrochlorothiazide and quinapril?

Tell your doctor about all your other medicines, especially:

  • any other blood pressure medication;
  • lithium;
  • everolimus, sirolimus, temsirolimus;
  • an antibiotic --demeclocycline, doxycycline, minocycline, eravacycline, omadacycline, sarecycline, tetracycline; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect hydrochlorothiazide and quinapril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about hydrochlorothiazide and quinapril.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2020 Cerner Multum, Inc. Version: 9.01. Revision date: 1/6/2020.

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